Observed and calculated cerebral critical closing pressure are highly correlated in preterm infants
نویسندگان
چکیده
منابع مشابه
Cerebral vasospasm affects arterial critical closing pressure.
The effect of cerebral vasospasm (CVS) after aneurysmal subarachnoid hemorrhage (SAH) on critical closing pressure (CrCP) has not been fully delineated. Using cerebral impedance methodology, we sought to assess the behavior of CrCP during CVS. As CrCP expresses the sum of intracranial pressure (ICP) and vascular wall tension, we also explored its role in reflecting changes in vascular tone occu...
متن کاملCerebral Oxygenation Is Highly Sensitive to Blood Pressure Variability in Sick Preterm Infants
OBJECTIVES The significance of blood pressure variability (BPV) for cerebral oxygenation in extremely preterm infants has not been explored, though BPV may well be associated with end organ injury. We hypothesized that increased BPV in sick preterm infants, by exceeding the cerebral autoregulatory capacity, is associated with cerebral oxygenation changes which closely follow the blood pressure ...
متن کاملCritical closing pressure explains cerebral hemodynamics during the Valsalva maneuver.
The Valsalva maneuver (VM), a voluntary increase in intrathoracic pressure of approximately 40 mmHg, has been used to examine cerebral autoregulation (CA). During phase IV of the VM there are pronounced changes in mean arterial blood pressure (MABP), pulse interval, and cerebral blood flow (CBF), but the changes in CBF are of a much greater magnitude than those seen in MABP, a finding to date a...
متن کاملCerebral oxygenation in preterm infants.
BACKGROUND AND OBJECTIVE Prone sleeping is a major risk factor for sudden infant death syndrome (SIDS) and preterm infants are at significantly increased risk. In term infants, prone sleeping is associated with reduced mean arterial pressure (MAP) and cerebral tissue oxygenation index (TOI). However, little is known about the effects of sleeping position on TOI and MAP in preterm infants. We ai...
متن کاملCerebral hypoxia and ischemia in preterm infants
Premature birth is a major public health issue internationally affecting 13 million babies worldwide. Hypoxia and ischemia is probably the commonest type of acquired brain damage in preterm infants. The clinical manifestations of hypoxic-ischemic injury in survivors of premature birth include a spectrum of cerebral palsy and intellectual disabilities. Until recently, the extensive brain abnorma...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 2019
ISSN: 0031-3998,1530-0447
DOI: 10.1038/s41390-019-0403-y